ISSUE: While most would agree that the patient perspective is an important aspect of value assessment, consensus is lacking on how to achieve this. Patient heterogeneity, individual preferences, and incorporation of indirect benefits have all been identified as potential solutions to the problem, but we fail to agree on the best approach going forward. Which solution is best? Are all required? Furthermore, we often stop short of understanding how to incorporate any of these solutions into actual value assessment tools. Michael Ciarametaro will moderate and provide an overview of the challenges associated with incorporating the patient perspective in value assessment. Ilene Hollin (patient preference researcher perspective) will address patient heterogeneity in terms of how patients think about value. David Wamble (indirect benefits researcher perspective) will speak to how assessments differ when considering indirect benefits in value assessment. Josh Seidman (framework developer perspective) will address how their patient-centered value assessment framework incorporates patient perspectives. OVERVIEW: Value assessment frameworks are becoming a tool increasingly used by decision-makers to evaluate the use of healthcare services. It is widely accepted that value assessment, an already complex pursuit, is complicated further by the inclusion of the patient perspective. Many argue that for value assessment tools to achieve maximum utility they should incorporate the patient point-of-view. Few agree, however, on the best way to achieve this goal. The list of challenges in doing so are long and include reconciling individual preferences and needs with population-level decision-making, accounting for long-term benefits on a short-term time horizon, and acknowledging indirect benefits in a healthcare system perspective that is traditionally aligned to consider more tangible clinical benefits. Lack of consensus about the appropriate approach puts us at risk for ignoring patient perspectives altogether. Continual debate as well as trial and error are necessary to ensure forward movement. This panel, with participation from the audience, will attempt to answer the question about what aspects of the patient perspective should be included in value assessment frameworks and how to best incorporate them.