THE COSTS OF INTENSIFYING TYPE 2 DIABETES PATIENTS TREATED WITH BASAL INSULIN TO BASAL IN COMBINATION WITH GLP-1- A PHYSICIAN SURVEY

Author(s)

Pfeiffer KM1, Basse A2, Brod M1
1The Brod Group, Mill Valley, CA, USA, 2Novo Nordisk A/S, Søborg, Denmark

OBJECTIVES : To examine physicians’ perspectives on the healthcare resources and time required to intensify type 2 diabetes (T2D) patients treated with basal insulin by adding GLP-1 receptor agonists (GLP-1). METHODS : Concept elicitation interviews with 16 physicians in the United Kingdom (UK) and United States (USA) were used to develop the web-based survey. Cognitive interviews were conducted with 12 additional physicians, and usability testing was completed prior to survey launch. In total, 458 physicians, including general practitioners (GPs) and specialists (diabetologists/endocrinologists), completed the survey. Physicians not experienced with intensifying basal insulin with GLP-1 were excluded from analysis (n=444; UK, n=216; USA, n=228). RESULTS : On average, physicians indicated that patients had 2.0 healthcare provider (HCP) visits [95% CI, 1.8-2.3] before agreeing or refusing to intensify with GLP-1, and this process took a mean of 8.4 weeks [95% CI, 7.7-9.1]. Physicians reported that 1.8 HCP visits [95% CI, 1.6-1.9] were needed for intensification training, on average, which took 5.3 weeks [95% CI, 4.8-5.8]. On average, an additional 1.9 HCP visits [95% CI, 1.8-2.0] were necessary for titration to an optimal dose after initial training, which took 9.8 weeks [95% CI, 9.2-10.5]. In total, 5.7 HCP visits [95% CI, 5.3-6.1] were required for intensification to basal with GLP-1, a process which took 23.5 weeks [95% CI, 22.1-25.0], on average excluding referral time. Among patients intensified with GLP-1, physicians reported that, on average, 58.5% reached their HbA1c target following 2.2 HCP visits [95% CI, 2.1-2.3] and 36.7% discontinued the intensified regimen

Conference/Value in Health Info

2018-05, ISPOR 2018, Baltimore, MD, USA

Value in Health, Vol. 21, S1 (May 2018)

Code

PDB43

Topic

Economic Evaluation

Topic Subcategory

Cost/Cost of Illness/Resource Use Studies

Disease

Diabetes/Endocrine/Metabolic Disorders

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