USE OF ECONOMIC EVIDENCE TO INFORM DRUG REIMBURSEMENT DECISION MAKING- THE CASE FOR ONTARIO

Author(s)

Syed S, Agarwal A, Xie F
McMaster University, Hamilton, ON, Canada

OBJECTIVES: The Ontario Drug Benefit (ODB) Formulary is the publicly funded provincial drug plan in Ontario. Drugs are included subsequent to a review of submitted clinical efficacy and pharmacoeconomic evidence by the Committee to Evaluate Drugs (CED). The objective of this analysis was to examine the degree to which economic evidence was utilized to inform drug reimbursement decision making in Ontario. METHODS: All publicly available CED “Recommendation and Rationale” documents were reviewed to classify type of economic evidence, CED recommendations and rationales.  Descriptiveand logistic regression analyses were conducted to examine the extent that economic evaluation impacts CED recommendations among other potential predictor factors. RESULTS: A total of 123 separate recommendations were retrieved (July 2007 to November 2012). Forty –seven percent received a fund recommendation while 53% received a do not fund recommendation. Almost all recommendations included some discussion of economic evidence; however complexity was limited to a discussion of price of therapy only for the majority (70%). Regression analysis found that documents including a discussion of economic evidence beyond price and statement of a price of therapy less than or similar to alternatives were more likely to result in positive recommendations (p < 0.05). CONCLUSIONS: Although economic evidence was routinely reviewed, discussion was usually limited to price of therapy. However, when pharmacoeconomic evidence beyond price alone was discussed, a  recommendation to fund by the CED was more likely.

Conference/Value in Health Info

2014-05, ISPOR 2014, Palais des Congres de Montreal

Value in Health, Vol. 17, No. 3 (May 2014)

Code

PHP49

Topic

Health Policy & Regulatory

Topic Subcategory

Reimbursement & Access Policy

Disease

Multiple Diseases

Explore Related HEOR by Topic


Your browser is out-of-date

ISPOR recommends that you update your browser for more security, speed and the best experience on ispor.org. Update my browser now

×