USE OF DIARY ALARMS ON ELECTRONIC DEVICES FOR COLLECTING DATA FROM MIGRAINE SUBJECTS WITH PHONOPHOBIA

Author(s)

Dallabrida SM, Gary ST
PHT Corporation, Boston, MA, USA

OBJECTIVES: Electronic Patient Reported Outcomes (ePRO) such as daily diaries are often used in migraine clinical trials to collect information regarding migraine frequency, duration, severity, and symptoms.  In general, alarms are an effective tool for prompting subjects to complete diaries on schedule.  However, 70-80% of migraineurs suffer from phonophobia during a migraine.  Thus, it is possible that an alarm may worsen symptoms.  To address this, a decibel meter was used to measure the sound level of alarms on three models of the PHT LogPad handheld electronic device, and readings were compared to published sound aversion thresholds (SAT) for migraineurs.   METHODS: The LogPad (LW, CV and LV) models were placed at a distance of one or five feet from the decibel meter.  Alarm sound was measured on two devices in triplicate at each sound setting. RESULTS: The SAT for migraineurs is reported to be approximately 76 decibels (db) (ictal) and 91 db (interictal).  Healthy subjects have a SAT of 105 db. When the LogPad LW and decibel meter were placed one foot apart, the decibel meter measured 58, 67, 75, and 83 db at the normal, medium, high and very high sound settings, respectively, and measured 76 db for the CV and 80 db for the LV models.  When any LogPad model was placed five feet away from the decibel meter, all readings were below the ictal SAT for migraineurs.   CONCLUSIONS: Even at a 1 foot distance, the alarm volume on the LogPad LW can be set below the ictal SAT for migraineurs and is also above background sound.  At a distance of 5 feet, all models tested are below SAT and above background.  Therefore, the LogPad is a suitable handheld electronic device to use with migraineurs that suffer from phonophobia with alarm volumes that can be used below SAT

Conference/Value in Health Info

2014-05, ISPOR 2014, Palais des Congres de Montreal

Value in Health, Vol. 17, No. 3 (May 2014)

Code

PND46

Topic

Patient-Centered Research

Topic Subcategory

Patient-reported Outcomes & Quality of Life Outcomes

Disease

Neurological Disorders

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