OBJECTIVES: Urinary incontinence (UI) is an undertreated condition. We examined the likelihood of receiving UI treatment in subjects having UI alone and UI along with different comorbidities. METHODS: This was a retrospective cross-sectional study of a 10% random sample of IMS LifeLink data from 2001-2011. Subjects were >= 18 years of age and continuously enrolled 6 months pre and post their first index diagnosis. UI subjects had at least two outpatient or one outpatient and one inpatient claims at least 7 days apart. Co-morbidities were observed in the pre- and post-index periods. Five mutually exclusive comorbidity groups were then formed:  UI alone, UI with multiple sclerosis or Parkinson’s diseases or stroke, UI with diabetes or cardiovascular diseases, UI with arthritis or respiratory diseases or inflammatory bowel disease or dementia, or UI with any other co-morbidities.  Treatment (Pharmacotherapy or behavioral therapy for UI) was observed 15 days pre- and 6 months post-index UI diagnosis. Logistic regression adjusted for region, age and Charlson comorbidity score was used to contrast these comorbidity groups on the likelihood of receiving treatment for UI. RESULTS: There were 4,374 (28.15 %) subjects with UI who received treatment, and 11,162 (71.85 %) with UI and did not receive treatment. The odds of receiving treatment was only influenced by those with multiple sclerosis, Parkinson’s diseases or stroke subjects for those with  (aOR = 1.46, p<0.001). CONCLUSIONS:  Current guidelines recommend treatment for UI in the presence of multiple sclerosis, Parkinson’s diseases or stroke and our data suggest that treatment resembles guideline recommendations.