THE IMPACT OF DAYTIME AND NOCTURNAL NON-SEVERE HYPOGLYCAEMIC EVENTS ON PEOPLE WITH DIABETES IN SINGAPORE

Author(s)

Jain A1, Todorova L2
1Novo Nordisk Pharma (Malaysia) Sdn. Bhd., Kuala Lampur, Malaysia, 2Novo Nordisk International Operations, Zurich, Switzerland

OBJECTIVES: To study the effect of nocturnal and daytime non-severe hypoglycaemic events on people with diabetes in Singapore. METHODS: People with diabetes from five countries, including Singapore, who had experienced a non-severe hypoglycaemic event in the 4 weeks prior to the survey were eligible. Both surveys were conducted face to face; all information, including hypoglycaemic events, was self-reported.  RESULTS: In the Singaporean cohort, 76 people responded (50 for the nocturnal survey [N]; 51 for the daytime survey [D]). Mean age was 54 years/56 years (N/D), mean weight was 63.2 kg/68.3 kg (N/D), 48%/49% (N/D) were male, and 70%/80% (N/D) had type 2 diabetes. Among respondents with type 2 diabetes, 11%/10% (N/D) received insulin and 100%/100% (N/D) received oral medication. Almost half of respondents had diabetes-related complications (46%/49% [N/D]), and 16%/18% (N/D) experienced hypoglycaemia at least once/week. When asked about hypoglycaemia awareness, 14%/14% (N/D) reported only noticing they were hypoglycaemic during routine blood glucose checks, while 8%/16% (N/D) were generally unaware of an event. After a hypoglycaemic event, 12%/20% contacted a healthcare professional and, in the following week, used on average 1.1/2.1 (N/D) extra blood glucose strips. Following a nocturnal event, mean time to return to sleep was 63 minutes; 24% reported difficulty returning to sleep after the event, almost two thirds (62%) felt tired and/or fatigued the next day, and 22% reported high level of fear of a future event. In the daytime survey, the most common measures taken in order to avoid hypoglycaemia were defensive snacking and avoiding exercise. Respondents reported spending most time worrying about feeling lightheaded/dizzy, having an event while alone, and passing out in public. CONCLUSIONS: In Singapore, hypoglycaemic events impact healthcare utilisation and daily routines for people with diabetes. Treatment strategies to decrease hypoglycaemia could offer substantial benefits to people with diabetes.

Conference/Value in Health Info

2014-05, ISPOR 2014, Palais des Congres de Montreal

Value in Health, Vol. 17, No. 3 (May 2014)

Code

PDB115

Topic

Patient-Centered Research

Topic Subcategory

Patient-reported Outcomes & Quality of Life Outcomes

Disease

Diabetes/Endocrine/Metabolic Disorders

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