OBJECTIVES: Created in 2002, the Patient-Reported Outcome and Quality of Life Instruments database (PROQOLID) provides a detailed description of 773 generic, disease-, and population-specific Patient-Centered Outcomes measures on the Internet (www.proqolid.org). The objective of this study was to find out if PROQOLID could help researchers identify questionnaires available in French for use in Quebec. METHODS: The PROQOLID database was explored on November 10, 2013 using the search engine and selecting in the language field the key words “French for Canada.” RESULTS: Two hundred and twelve questionnaires were identified representing 27.42% of the instruments available in PROQOLID [in comparison, 383 questionnaires (49.54%) were available in French for France]. Out of these 212 questionnaires, 26 were generic. Twenty different therapeutic areas were identified (e.g., endocrine system diseases, neoplasms, nervous system diseases, respiratory tract diseases, or psychiatric disorders), representing 75 different indications, and 83.33% of the therapeutic areas included in PROQOLID (n=24). Twenty-three questionnaires were available for pediatric use (children and/or adolescents), either generic [e.g., Pediatric Quality of Life Inventory Generic Core (PedsQL)], or disease-specific [e.g., Paediatric Asthma Quality of Life Questionnaire (PAQLQ)]. Asthma and diabetes mellitus were the most frequent indications (16 questionnaires available for each indication), followed by dementia (including Alzheimer’s disease) and dyspepsia (eight questionnaires for each indication), pain (seven questionnaires), and sleep disorders (six questionnaires). Within the therapeutic area of neoplasms, five different indications were identified (brain, breast, lung, myeloma and ovary), and seven questionnaires for generic use [e.g., EORTC Quality of Life Questionnaire - Core Questionnaire (EORTC QLQ-C30), Functional Living Index – Cancer (FLIC)]. Not a single instrument was identified in therapeutic areas such as bacterial infections and mycoses; congenital, hereditary diseases; stomatognathic diseases; and surgical procedures. CONCLUSIONS: This overview showed that Patient-Centered Outcome measures available for use in Quebec cover a wide variety of indications.