OBJECTIVES: To describe changing diabetes treatment pattern among the elderly type 2 diabetes (T2DM) patients during the past 7 years. METHODS: A large retrospective Medicare patient claims data (MarketScan® Medicare) was longitudinally analyzed from 2005 to 2011 to understand T2DM medication use trend.  The study included 4 major oral antidiabetic medications (i.e., metformin (MET), sulphonylurea (SU), thiazolidinediones (TZD), and dipeptidyl peptidase 4 inhibitor (DPP-4)) plus injectables (insulin and glucagon-like peptide