OBJECTIVES: The study has been set-up in order to evaluate in real life conditions the perceived efficacy of a spray containing essential oils on allergy-related-symptoms, day-sleepiness and QoL of allergic subjects. METHODS: Women-and-men with a known history of dust mite allergy were recruited in the study. They were asked to use in their house twice a day, the purifier spray for a period of 28days. The perceived efficacy was evaluated via self-validated questionnaires on allergy symptoms (discomfort generated by sneezing- itchy eyes-stuffy nose-nasal flow-tiredness-ear itching), on daytime-sleepiness (Epworth-Sleepiness-Scale) and on QoL (SF12). For the study outcomes, each subject was evaluated at inclusion, at day7 and day28. The satisfaction through the CSQ8-questionnaire was also evaluated at day28. RESULTS: