OBJECTIVES: Prescription drug monitoring programs (PDMPs) are viewed as an effective tool to reduce prescription drug abuse, diversion, and doctor shopping. Despite perceived effectiveness, PDMP utilization by healthcare providers remains low. To improve effectiveness, healthcare professionals must access and utilize PDMP reports when making treatment decisions. Understanding characteristics of PDMPs users may assist in developing strategies to increase utilization. We identify characteristics of community pharmacists in Kentucky who utilize the Kentucky All Schedule Prescription Electronic Reporting (KASPER) program and determine if perceptions regarding KASPER’s impact and effectiveness are related to pharmacists’ characteristics. METHODS: Surveys were mailed to 2,018 Kentucky pharmacists. Reminder postcards and surveys were sent two weeks after the initial mailing. Bivariate analyses examined relationships between respondent characteristics and practice site (independent versus chain) and practice location (rural versus urban). Logistic regression models (LRM) adjusted for years since licensure, controlled substance (CS) dispensing volume, and perceived KASPER effectiveness estimated the odds ratio (OR) and 95% confidence intervals (CI) of KASPER utilization by community pharmacists. Statistical analyses were conducted in Stata v12.0. The study was approved by the University of Kentucky Institutional Review Board. RESULTS: Responses from 411 community pharmacists were included in the analysis. Results from LRM show that KASPER use varies significantly. Community pharmacists practicing in urban locations are 2.25 times more likely (CI: 1.11-4.57) to utilize KASPER than pharmacists in rural locations. Additionally, pharmacists practicing at independent pharmacies are 7.60 times more likely (CI: 3.20-18.05) to use KASPER than their counterparts practicing at chain pharmacies. The volume of CS dispensed nor perceived effectiveness of KASPER influenced the odds of KASPER utilization. CONCLUSIONS: Among community pharmacists, KASPER utilization varies and is influenced by pharmacists’ characteristics including practice site and practice location. Understanding characteristics of pharmacists who utilize PDMPs is necessary to remove barriers to access and increase utilization.