OBJECTIVES:   As a Medicaid managed care organization (MCO), Keystone First experiences a high volume of pediatric members receiving care for common childhood illnesses at hospital emergency departments (EDs). The 4 Your Kids Care program educates parents/caregivers about what to do when their children get sick, encourages members to engage their primary care physicians, and refers families to appropriate plan resources (e.g., 24/7 Nurse Hotline and Care Management). METHODS: A 2.5-hour program educates parents/caregivers about treating common pediatric illnesses at home. The study group (SG) consisted of participating parents/caregivers of 585 pediatric members (≤5 years old) in Philadelphia and Delaware counties (Pennsylvania) with at least one prior-year non-emergent ED claim. The matched control group (CG) consisted of 1,189 pediatric members with nonparticipating parents/caregivers in the pre-period and 1,153 in the post-period. The baseline period (January 1, 2010–December 31, 2010) where non-urgent ED claims were collected was followed by the class period (January 1, 2011–September 30, 2011) and one-year follow-up period (October 1, 2011–December 31, 2012). Participants completed a knowledge assessment both before commencement and after completion of the class. RESULTS: While the average number of ED visits for non-urgent conditions decreased significantly during the 12-month period in SG (p<0.0001) and CG (p=0.0097), the mean reduction for SG was more than three-fold greater than CG (-46.3% vs. -14.6%, respectively). Amounts paid for ED claims for non-urgent visits during the 12-month period for SG decreased by over twice the amount of CG (-37.8% vs. -17.4%). Questionnaire respondents displayed significant improvements in all six questions regarding knowledge assessment (p<0.01). Participant evaluations of the program were overwhelmingly favorable. CONCLUSIONS: