OBJECTIVES:  The Total Parenteral nutrition (TPN) services is a part of the pharmacy strategic planning at MOH in Saudi Arabia. The study explored the workload analysis of public hospital in Riyadh city, Saudi Arabia METHODS: RESULTS:  The total number patients were 112 with 1631 TPN orders. Of that 1464 TPN orders for 108 neonates patients, 39 TPN orders for three pediatrics patients, and 108 TPN orders for six adults patients. The Average number of TPN preparations per day for adults 0.6 order, pediatrics 0.22 order, and neonates 8.24 orders. The average volume per the order for adults was 1,822.96 ml for Pediatrics 1,116.41 ml and neonates 255.22 ml. The average time preparation per each preparation 35 min. The Total full-time employee (FTE) for TPN services (1.51 FTE) pharmacist per day. It divided toTPN central pharmacy services (0.3 FTE) pharmacist, TPN patient specific pharmacy activities (1.18 FTE) pharmacist, and TPN administration specific pharmacy activities (0.019 FTE) pharmacist CONCLUSIONS:  The workload analysis of Total Parenteral Nutrition is the first study at MOH in Saudi Arabia. It is an essential tool for quality indicators of TPN services, and pharmacy strategic plan, forecasting of new TPN services.