TREATMENT OF UPPER-EXTREMITY SARCOMA WITH LIMB-SALVAGE PROCEDURES SHOWED GOOD FUNCTIONAL OUTCOMES- A PILOT STUDY OF 13 CONSECUTIVE PATIENTS

Author(s)

Repo JP, Barner-Rasmussen I, Kask G, Blomqvist C, Tukiainen EJ
University of Helsinki and Helsinki University Hospital, Helsinki, Finland

OBJECTIVES: Achieving optimal functional capability after limb-salvage procedures in the treatment of upper-extremity sarcoma is of high importance. The present pilot study aimed to assess the upper-extremity functional and disability levels using patient-centered outcomes among patients who underwent upper-extremity sarcoma treatment with limb-salvage procedures. METHODS: Between March and May 2015, the authors recruited 13 consecutive patients (mean age 59 years) who had undergone upper-extremity limb-salvage procedures for various types of soft-tissue sarcomas. The malignancy located either in the antebrachium (n=8), the brachium (n=2) or the shoulder (n=3). Five patients underwent myectomy and the remaining eight patients had their tumor excised. Six excision wounds were primarily closed, four patients underwent reconstruction with split-skin grafting, ant the three remaining patients had free flap transfer. Patients completed the Toronto Extremity Salvage Score (TESS) for patient-reported functional assessment and their upper-extremity disability level was assessed using the clinician-administered Musculoskeletal Tumor Society (MSTS) instrument. Primary outcomes were mean total scores in the TESS and MSTS rating scales. RESULTS: The mean follow-up time was 2.2 years. The analysis of the outcomes revealed a mean (SD) TESS score of 136 (22) points from the maximum score of 150 points, indicating a mean of 91% function of the upper-extremity. The MSTS rating scale revealed a mean score of 26 (6) points from the maximum of 30 points, showing a mean of 13% upper-extremity disability level. CONCLUSIONS: The present study found that functional outcomes ranging from fair to excellent were achieved when limb-salvage procedures are used in the treatment of upper-extremity sarcoma. Further studies with larger study samples are needed to assess the true nature of functional outcomes after upper-extremity sarcoma limb-salvage procedures.

Conference/Value in Health Info

2016-10, ISPOR Europe 2016, Vienna, Austria

Value in Health, Vol. 19, No. 7 (November 2016)

Code

PCN212

Topic

Patient-Centered Research

Topic Subcategory

Patient-reported Outcomes & Quality of Life Outcomes

Disease

Oncology

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