TREATMENT OF UPPER-EXTREMITY SARCOMA WITH LIMB-SALVAGE PROCEDURES SHOWED GOOD FUNCTIONAL OUTCOMES- A PILOT STUDY OF 13 CONSECUTIVE PATIENTS
Author(s)
Repo JP, Barner-Rasmussen I, Kask G, Blomqvist C, Tukiainen EJ
University of Helsinki and Helsinki University Hospital, Helsinki, Finland
OBJECTIVES: Achieving optimal functional capability after limb-salvage procedures in the treatment of upper-extremity sarcoma is of high importance. The present pilot study aimed to assess the upper-extremity functional and disability levels using patient-centered outcomes among patients who underwent upper-extremity sarcoma treatment with limb-salvage procedures. METHODS: Between March and May 2015, the authors recruited 13 consecutive patients (mean age 59 years) who had undergone upper-extremity limb-salvage procedures for various types of soft-tissue sarcomas. The malignancy located either in the antebrachium (n=8), the brachium (n=2) or the shoulder (n=3). Five patients underwent myectomy and the remaining eight patients had their tumor excised. Six excision wounds were primarily closed, four patients underwent reconstruction with split-skin grafting, ant the three remaining patients had free flap transfer. Patients completed the Toronto Extremity Salvage Score (TESS) for patient-reported functional assessment and their upper-extremity disability level was assessed using the clinician-administered Musculoskeletal Tumor Society (MSTS) instrument. Primary outcomes were mean total scores in the TESS and MSTS rating scales. RESULTS: The mean follow-up time was 2.2 years. The analysis of the outcomes revealed a mean (SD) TESS score of 136 (22) points from the maximum score of 150 points, indicating a mean of 91% function of the upper-extremity. The MSTS rating scale revealed a mean score of 26 (6) points from the maximum of 30 points, showing a mean of 13% upper-extremity disability level. CONCLUSIONS: The present study found that functional outcomes ranging from fair to excellent were achieved when limb-salvage procedures are used in the treatment of upper-extremity sarcoma. Further studies with larger study samples are needed to assess the true nature of functional outcomes after upper-extremity sarcoma limb-salvage procedures.
Conference/Value in Health Info
2016-10, ISPOR Europe 2016, Vienna, Austria
Value in Health, Vol. 19, No. 7 (November 2016)
Code
PCN212
Topic
Patient-Centered Research
Topic Subcategory
Patient-reported Outcomes & Quality of Life Outcomes
Disease
Oncology