OBJECTIVES:  Evaluation of cardiovascular disease (CVD) risk factors is crucial for the treatment of dyslipidemia patients, but little is known about its prevalence and CVD risk levels in this patient group. It aimed to assess CVD risk levels among patients on statin. METHODS:  We conducted a cross-sectional, multicenter and observational study in patients on statin for at least six months, but less than two years, from nationwide 26 tertiary hospitals in Korea between December 2014 and October 2015. Data was collected through self-administered questionnaires and medical chart review. CVD risk levels were categorized as low; 0-1 CVD risk factor from conventional criteria, moderate; 2+ CVD risk factors, high; CVD or CVD risk equivalents, very high; presence of CVD and one of followings; diabetes, smoking, multiple risk factors for the metabolic syndrome or acute coronary syndrome. RESULTS:  A total of 2,409 patients on statin treatment were enrolled in the study. The mean age was 62.4±11.2 years old, and 66.5% were male. More than half were classified as very high CVD risk level (51.5%), the second leading CVD risk level was high (29.9%), and moderate and low CVD risk levels were consisted of 13.5% and 5.1% respectively. Of the total, 15.2% were current smokers, 36.9% were current drinkers and about one third had never regular exercise. Of the total, 74.5% were taking antihypertensive medication, and 15.0% had the family history of premature CVD. Almost all the patients were co-morbid (Hypertension: 56.7%, Angina: 46.2%, Diabetes Mellitus: 25.1%, Myocardial Infarction: 24.9%). Prescribed dose of statin was different according to the CVD risk levels, and approximately 3/4 patients were prescribed with moderate intensity of statin in all risk levels (p<0.0001). CONCLUSIONS:  This study revealed that Korean patients on stain had high prevalence of CVD risk factors and a majority of the patients were at high or very high CVD risk levels.