OBJECTIVES: Cardiovascular drugs are the most utilised drugs in volume and the second most utilised drugs in sales. The overall number of drugs from ATC groups C03, C07, C08 and C09 reimbursed from the public insurance has increased by 62.72% (180 drugs) from 2008. The aim of our analysis was to evaluate the price-trend of the most utilised antihypertensives. METHODS: We identified the most utilised antihypertensives from C03, C07, C08 and C09 during 2008-2014. For these molecules, we have performed a financial analysis including all drugs reimbursed during the assessed period. The evaluated parameters were: average final price (AFP/DDD), co-payment (AC-P/DDD) and reimbursement (AR/DDD) per DDD. RESULTS: The highest utilisation within C03 reached furosemide (20.75 DID), indapamide (10.28 DID) and hydrochlorothiazide (3.12 DID); within C07 bisoprolol (17.94 DID), metoprolol (15.67 DID), carvedilol (6.39 DID); within C08 amlodipine (48.56 DID), nitrendipine (9.71 DID), verapamil (6.84 DID); and within C09 ramipril (29.62 DID), perindopril arginine (21.91 DID) and trandolapril (20.48 DID). The AFP/DDD, AC-P/DDD and AR/DDD decreased for furosemide, indapamide, carvedilol amlodipine and trandolapril. For bisoprolol, metoprolol, nitredipine, verapamil and perindopril arginine, a decrease in AFP/DDD and AR/DDD together with an increase in AC-P/DDD were observed. Only for hydrochlorothiazide and ramipril AFP/DDD increased. Whereas in the case of hydrochlorothiazide it was reflected in and increasing AR/DDD leaving the AC-P/DDD at zero, for ramipril it was fully translated into the increasing AC-P/DDD. CONCLUSIONS: The AFP/DDD was mostly steadily decreasing. There is an even distribution of drugs, for which the decreasing AFP/DDD was solely translated into the decrease of AR/DDD and drugs, for which it was reflected in decreasing AR/DDD and AC-P/DDD simultaneously. For the later, the AR/DDD-decrease was higher that the AC-P/DDD-decrease. Hence, the decreasing AFP/DDD of antihypertensives was primarily translated into the decrease of AR/DDD only secondarily into the decrease of AC-P/DDD.