OBJECTIVES: The ability to detect clinically meaningful change from the patients’ perspective is critical to evaluating new techniques and technologies for facial aesthetic patients. The FACE-Q is a new patient-reported outcome (PRO) instrument composed of scales that measure outcomes for patients having any type of facial cosmetic surgery, procedure or facial injectable. The objective of our study was to determine the responsiveness of the FACE-Q scale entitled “Satisfaction with Facial Appearance”. METHODS: The Satisfaction with Facial Appearance scale is composed of 10 items that ask about satisfaction using descriptors (e.g., symmetry; proportion) as well as scenarios (e.g., in photos; bright lights). Data were collected from 489 patients in Canada and the USA between June 2010 -2012 (response rate 78%).  Responsiveness was examined in 97 facelift patients by comparing pre and post- treatment Rasch transformed scores (range 0-100) using paired t-tests and calculating Kazis’ effect size and the standardized response mean. In addition, a change score for each patient was computed and categorized into 5 groups depending on the size and direction of their change score. RESULTS: Participants ranged in age from 37-77 years; 10 were male, 86 female. FACE-Q scores were significantly higher following a facelift (mean, SD; pre 45,16 vs. post 56, 21 respectively, p<0.0001). These scores were associated with ‘moderate’ effect sizes (ES = 0.68, SRM = 0.50). Preliminary MID analyses suggested an 8 point difference in total scores. This difference was exceeded in our analysis (mean change, SD = 11, 22). For individual-level findings, 94 out of 97 face-lift patients reported significant improvement in satisfaction with facial appearance. CONCLUSIONS: The FACE-Q scale ‘Satisfaction with Facial Appearance’ is capable of detecting clinically important change in facelift patients. Further responsiveness research is now needed with other facial aesthetics patient groups to add to the evidence base for the use of this scale.