IMPACT OF NON-SEVERE HYPOGLYCAEMIC EVENTS ON PATIENT WELL-BEING AND HEALTHCARE RESOURCE USE

Author(s)

Kulzer B1;Seitz L*2, Kern W3 1Forschungsinstitut Diabetes-Akademie, Bad Mergentheim, Germany, 2Novo Nordisk Pharma GmbH, Mainz, Germany, 3Endokrinologikum, Ulm, Germany

OBJECTIVES: Hypoglycaemia is a frequent side effect of insulin treatment for patients with diabetes and can impact on quality of life, well-being, work productivity and healthcare resources. This study explored patient-reported frequency of non-severe hypoglycaemic events (NSHE) and the impacts of these events on patients’ lives and healthcare resource use in Germany. METHODS: Patients over 15 years of age with Type 1 (T1) or insulin-treated Type 2 (T2) (basal only T2BOT; basal-bolus T2BB and other regimen T2O) diabetes were recruited in Germany via online panels to complete four questionnaires at weekly intervals. Data were collected on hypoglycaemia‑related resource use and the impact of the last hypoglycaemic event on patient well-being and work productivity. NSHE was an event with symptoms of hypoglycaemia, with or without blood glucose measurement (BGM), or low BGM (≤ 3.1 mmol/l) without symptoms, which the patient could manage without assistance. RESULTS: In total, 614 patients (34% T1 and 66% T2) participated in the study. Overall self-reported mean NSHE were 1.0 per patient week (1.6 for T1, 0.6 in T2BOT, 0.6 in T2BB and 0.8 in T2O). Following the last NSHE, 64% of patients reported feeling tired/fatigued with 51% and 39% feeling less alert and nervous/anxious, respectively. Overall employment rate was 53%. A total of 14% of patients reported loss of work time due to the last NSHE. Mean increase in BG test-strips use was 3.86 over the 7 days following each NSHE equating to an estimated additional resource use of €2/patient/event (cost/strip €0.5). Following a daytime NSHE 14% of T1 and 23% of T2 patients contacted a healthcare professional (nurse/physician), plus 16% of T1 and 13% of T2 patients following night-time events. CONCLUSIONS: NSHE have a negative impact on patient well-being and are associated with work time loss and increased use of healthcare resources in Germany.

Conference/Value in Health Info

2013-05, ISPOR 2013, New Orleans, LA, USA

Value in Health, Vol. 16, No. 3 (May 2013)

Code

PDB59

Topic

Economic Evaluation

Topic Subcategory

Cost/Cost of Illness/Resource Use Studies

Disease

Diabetes/Endocrine/Metabolic Disorders

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