OBJECTIVES: Diabetic foot ulcer (DFU) is a common complication of diabetes and not only an important factor of mortality among patients with diabetes but also a cause of decreased quality of life. The Diabetic Foot Ulcer Scale (DFS) and short form of the DFS (DFS-SF) provide comprehensive measurement of the impact of diabetic foot ulcers on patients’ QoL. The purpose of this study was to translate DFS-SF into Polish and evaluate its psychometric performance in patients with diabetic foot ulcers. METHODS:  DFS-SF translation process was performed in line with Principles of Good Practice for the Translation and Cultural Adaptation Process for PROMs developed by ISPOR TCA group. Assessment of the reliability and validity of Polish DFS-SF was performed in native Polish patients with current DFU. The severity of ulcers was evaluated using the PEDIS scale. For each scale, the item convergent validity and discriminant validity was computed. Internal consistency of each subscale was examined using the Cronbach’s alpha coefficient. Inter-scale validity was examined by Spearman’s rank correlation coefficient between DFS-SF and SF-36v2. RESULTS:  The DFS-SF validation study involved 212 patients diagnosed with DFU, with 4.4 years of DFU duration on average. The average ulcer size was 7.0 sq cm, and generally only one limb was affected. Men (72%) and type 2 diabetes patients (86%) prevailed, with 17.8 years representing the mean time since diagnosis. The mean population age was 62.5 years. The internal consistency of all scales of the Polish DFS-SF was high (Cronbach’s alpha ranged from 0.83 to 0.94). Item convergent and discriminant validity was satisfactory (median corrected item-scale correlation ranged from 0.61 to 0.81). The Polish DFS-SF demonstrated good construct validity when correlated with the SF-36v2. CONCLUSIONS: The newly translated Polish DFS-SF may be used to assess the impact of DFU on HRQoL in Polish patients.