OBJECTIVES: One of the main modifiable risk factors is the blood lipid levels, due to changes in lifestyle and treatment. The aim of this study is to characterize total cholesterol, low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) levels in adults with hypertension, diabetes, HT and DM, and CKD, reported to Cuenta de Alto Costo, 2014. METHODS: Descriptive and retrospective study. The information was obtained from the medical records of approx. 53 health insurance companies in Colombia. Data from 2.995.061 patients was used. Stata 13 was used for data analysis. Qualitative variables were described by its frequency distribution. RESULTS: CONCLUSIONS: patients with both diseases (HT and DM) had better LDL and TC levels than patients with other diseases, however HDL-C levels under 40mg/dl were higher in this patients group.