THE RHEUMATOLOGIST'S PERSPECTIVE IN DIAGNOSTIC COURSE AND MANAGEMENT OF FAMILIAL MEDITERRANEAN FEVER
Author(s)
Karadag O1, Kilic L2, Erden A1, Kasifoglu T3, Karaaslan Y4, Kiraz S1, Dokuyucu O5
1Hacettepe University, Ankara, Turkey, 2Yenimahalle Research Hospital, Ankara, Turkey, 3Eskisehir Osmangazi University Medical School, Eskisehir, Turkey, 4Ankara Numune Research Hospital, Ankara, Turkey, 5Novartis, Istanbul, Turkey
OBJECTIVES: To investigate the global perspectives of Turkish Rheumatologists regarding expected FMF prevalence, undiagnosed patients ratio, arguments in diagnostic procedure and management of FMF. METHODS: A questionnaire consist of estimated frequency, diagnostic modalities and follow up characteristics in addition to therapeutic approach was set up. Even though a regular colchicine use, ≥1 attack /month during 6 months was accepted as colchicine resistant. All members of Turkey Society for Rheumatology from country wide (n=235) were invited to fill in the web-based questionnaire for FMF by e-mail. Totally 108 members (45.9%) answered the questionnaire. RESULTS: Estimated prevalence was median 0.2% (IQR25-75: 0.1-0.7) for FMF. Only 51.4±19.0 % of these patients had been diagnosed according to Rheumatologists opinion. Time to diagnosis from the first symptom was more than 3 years in 49.5% of patients. Description of typical attacks in anamnesis is the most frequent parameter in diagnosis of patients whereas in 26.7 %of patients MEFV mutations were required for diagnosis.
Conference/Value in Health Info
2015-11, ISPOR Europe 2015, Milan, Italy
Value in Health, Vol. 18, No. 7 (November 2015)
Code
PSY102
Topic
Health Service Delivery & Process of Care
Topic Subcategory
Prescribing Behavior, Treatment Patterns and Guidelines
Disease
Rare and Orphan Diseases, Systemic Disorders/Conditions