OBJECTIVES: The factors which determine health services utilization (HSU) and access to health services are at the epicentre of health policy discussions, in an attempt to identify  barriers to access.   This study aims to investigate the factors that act as determinants of HSU for the Greek population, as well as highlight their evolution since 2006.  METHODS: The study was based on data collected by three cross-sectional health interview surveys conducted by the National School of Public Health, Athens, Greece, in 2006, 2011 and 2015 with representative national samples of 4003, 6569 and 2012 adults respectively.  Respondents were asked to answer a series of questions on HSU and report their demographic characteristics. RESULTS: A significant decrease in the basic measures of HSU between 2006 and 2015 was detected. In 2006, 74.6% of respondents answered that they had used a health service in the last 12 months, whereas in 2015 the corresponding figure was only 46.5%. There was a statistically significant association between HSU and gender of respondents, with females utilizing the services at a considerably higher rate (52.9%) than men (38.6%). The degree of non utilization health services was not changed substantially in these surveys,  however the reasons for not using the services were found to change and brought up statistically significant associations with age, income and occupation of respondents. It is noteworthy that the percentage of population unable to access healthcare due to inability to pay was 5.9%, 8.5% and 27.4% in 2006, 2011 and 2015 respectively.      CONCLUSIONS: It is evident that demographic and socioeconomic determinants influence the  HSU. The findings highlight the problem of social inequalities as a major issue of health policy.