OBJECTIVES: Pharmacists, working as part of the multidisciplinary team, have a relevant role in improving clinical outcomes through providing educational intervention, medicine management intervention, or a combination of both. The purpose of this study was to determinate the impact of a telephone counseling intervention administered bi-monthly by pharmacist on patients’ beliefs about antihypertensive medicines and blood pressure control. METHODS: Subjects were selected on a time frame of two months according to their attendance to the Centre for the Diagnosis and Therapy of Arterial Hypertension of Cardarelli Hospital of Naples, located in the South of Italy. Participants were randomly assigned to either control group (usual care) or intervention group (educational intervention). The study was developed in the framework of the Multidisciplinary Health Care Team (GOIP) for Diagnosis and Therapy of Arterial Hypertension activities. The intervention consisted of an educational/counseling session based on patients’ needs assessment and provided by a pharmacist bi-monthly for one year via telephone. RESULTS: A total of 164 patients (80 in the control group, CG, and 84 in the intervention group, IG) were recruited.  At the end of follow-up, the reduction in SBP and DPB was significant in IG (p<0.001) and  there were also significant differences between IG and CG for both Necessity and Concern score (t=5.74, p<0.001; t=-7.86,  p<0.001 respectively ). Patients were divided into four attitudinal groups based on their BMQ results and data showed that at t=12 83,3% of IG patients was “Accepting” and 15.5% was “Ambivalent”. None “Skeptical” patients were found in the IG and only 1,2% was “Indifferent”. CONCLUSIONS: Telephone-administered pharmacist intervention can improve BP control modifying patients beliefs and concerns about treatments, as well as involving patients as participants in the management of their health.