OBJECTIVES: The standardized incidence of kidney cancer (KC) in Slovakia was 14,6/100 000 in men and 7,0/100 000 in women and has growing trend. There were diagnosed more than 800 new cases in 2013 of KC in Slovakia. The objective of this paper was to find out the level of QoL in patients with KC in Slovakia. METHODS: The primary method used for the analysis of QoL was the combined questionnaire consisting of 6 parts: A. Demography (9 items), B. Clinical part (B1+B2, 17 items), C. Quality fo life with dominant numeric scale (13 items), D. Socio-economic part (9 items), E. EQ-5D (5 items), F. Symptoms of disease (9 items). There were 79 patients in the examined group from the110 asked to fill the questionnaire. All patients were treated by surgery. RESULTS: Present level of QoL was identified as 6,32 on the scale from 0 to 10 (0- the worst,10 -thebest), while in the time of the KC diagnosis it was 5,15. QoL was 7,86 in the time without BC and 8,82 in the total optimal state of health. Comparative to the QoL was examined the ability to work (AW), too. Present level of AW was identified as 6,02, while in the time of the BC diagnosis it was 5,44. AW was 8.25 in the time without KC and 9,06 in the total optimal state of health.  The impact of treatment on QoL was 6,34 and the disease had impact 5,94 on family QoL. The average income was 456 € and the willingness to pay for 1 month was in average 270 € per months to be complete healthy. CONCLUSIONS: The disease had a significant impact on patients´s QoL  nad patient´s family QoL, too. The treatment of BC had a significant impact on increasing QoL of patients.