OBJECTIVES: The standardized incidence of women breast cancer (BC) in Slovakia is 51,6/100 000 and has growing trend. There were diagnosed 2423 new cases in 2012 and 2639 new cases BC in Slovakia. BC has a  great impact on quality of life (QoL). The objective of this paper was to find out the level of QoL in patients with BC in Slovakia. METHODS: The primary method used for the analysis of QoL was the combined questionnaire consisting of 5 parts: A. Demography (9 items), B. Clinical part (B1+B2, 17 items), C. Quality fo life with dominant numeric scale (13 items), D. Socio-economic part (9 items), E. EQ-5D. There were 112 patients in the examined group from the 150 asked to fill the questionnaire.  RESULTS: Present level of QoL was identified as 6,11 on the scale from 0 to 10, while in the time of the BC diagnosis it was 4,42. QoL was 8.22 in the time without BC and 8,73 in the total optimal state of health. Comparative to the QoL was examined the ability to work (AW) and so on the scale from 0 to 10. Present level of AW was identified as 5,40, while in the time of the BC diagnosis it was 4,44. AW was 8.41 in the time without BC and 9,00 in the total optimal state of health.  The impact of treatment on QoL was 5,38 and the disease had impact 6,10 on family QoL. Disability was 77,35 days  vs 16,45 opposite to disabilities days from other reasons. The average income was 379,58 € and the willingness to pay for 1 month of full health was in average 132 € per months. CONCLUSIONS: The disease had a significant impact on patients´s QoL . The treatment of BC had a significant impact on increasing QoL of patients.