OBJECTIVES: To study the pattern of prescription of antihypertensive agents among the patients visiting Cardiology department METHODS: This is a cross sectional study conducted in collaboration with Department of Cardiology, College of Medical Sciences and Teaching Hospital, Bharatpur, Chitwan during the period of three months (1^st January to 31^st March 2015). All the patients attending the outpatient department of Cardiology and prescribed antihypertensive drugs were taken as sample.  RESULTS: Among the total 382 patients studied, the mean age was 58.53 ± 12.295 years. Males contributed to 219 (57.32%) and females 163 (42.67%) cases. Mean body mass index was 23.64 ± 5.29 Kg/m CONCLUSIONS: The above findings would be useful for physicians and clinical pharmacologists in evaluating rational prescribing of the antihypertensive medicines. The inadequacy of control of blood pressure by monotherapy has increased the trend for combination therapy. The common antihypertensive used were angiotensin receptor antagonists.