OBJECTIVES: This study aimed to identify factors affecting community pharmacy performance and identify important items in assessing community pharmacy performance, with emphasize on Iran setting. METHODS: In 2014, a cross-sectional survey was conducted through a survey using a self-administered, anonymous questionnaire. The target population of this study included pharmacists involved in managing a community pharmacy, in Iran, at least for 3 years by the time of the study. The questionnaire was developed and revised based on the related literature and experts’ opinions. The obtained questionnaire consisted of 3 parts, including factors influencing community pharmacy performance, items proposed for evaluating the performance of a community pharmacy, and respondents’ demographics, respectively. Five point Likert scale was used in the first two sections. SPSS 16.0.0 was used to perform descriptive analysis of respondents’ demographics and factor analysis of other data. The importance of each dimension was expressed as the standardized coefficients calculated by LISREL 8.50. RESULTS: