OBJECTIVES: Ghana has documented recurrent Cholera outbreaks (Davies-Teye, 2014); the worst ever in 2014 had high case, death incidence and yet does not routinely audit these deaths. Auditing the deaths would improve healthcare quality delivered to clients This study aimed at developing standardized Cholera Death audit tool,  describe the deaths and identify prevalent factors that contributed to deaths. METHODS: Standardized cholera death audit tool was developed. Census of cholera deaths from June – December 2014 in Greater Accra Region made. Medical records, surveillance data of deaths from treatment centers reviewed with the developed audit tool. Data abstracted included socio-demographic, clinical, patient monitoring. Data managed in Epi info7. Descriptive, bivariate analysis made and Prevalent Odds Ratio (95% Confidence Interval) determined to identify prevalent factors associated with deaths. RESULTS: The region documented 20,199 (Attack rate 432 per 100,000 populations) cholera cases with 121 deaths (CFR 0.60%). La Nkwantanang-Madina and Ladade Kotopon were most affected with Attack rates above 600 per 100,000 populations. Ada East, Ashaiman and LEKMA had case fatalities above 0.9%. Ages ranged 1–82 years, mean 41.0 ±17, median 39.0, mode 24.0 years. Males constituted 65.7% and 90.9% did not have health insurance. Duration of home stay ranged 0-5days. Nineteen percent were dead on arrival and 20.2% within 4hours of arrival.    Fifty one percent severely dehydrated with Systolic BP ranged 0.0–160.0mmHg, median 90.0mmHg. Diastolic BP ranged 0.0-110.0 mmHg, median 60.0mmHg. Total fluids given ranged 0.0–13.9 L, median 5.2 L. Only 1.4% had fluid output monitored. Lacking health insurance (POR=2.52, CI