OBJECTIVES: Comprehensive assessment of the financial costs of drug treatment of nonalcoholic steatohepatitis (NASH) in a hospital of Kharkiv, Ukraine.  METHODS: For the study, the schemes medicinal histories of 54 patients with NASH in a hospital in Kharkov during 2013 were used. The structure of costs of NASH treatment was assessed by the АВС analysis. Assessment of the level of NASH treatment correspondence was conducted by the formal VEN analysis according to the National Drug Formulary (NDF) of Ukraine (2013). Index “V” was put in case of availability of the drug in the NDF, index “N” – in case of its absence. Directions of NASH treatment were assessed by the prescriptions of drugs according to requirements of Ukrainian Cinical Guidelines (О.Ia. Babak, 2007) and according to Practice Guideline by the American Association for the Study of Liver Diseases (AASLD) for 2012. In determining the cost of drugs, their prices as of May 2015 by the data of Morion reference and retrieval system “Drugs” were used. RESULTS: Drug treatment of patients with NASH by pharmacotherapeutic groups met the basic requirements of Ukrainian Clinical Guidelines and Guidelines of American scientists AASLD, which confirms the rationality of prescriptions. According to the АВС/VEN analysis, most of the funds for treatment (82%) were spent on 76% of drugs included in the NDF. But 24% of drugs were missing from the NDF of Ukraine, indicating the need to correct NASH treatment in the hospital of Ukraine.  CONCLUSIONS: