OBJECTIVES: VTE (venous thromboembolism) are among the frequently associated with malignant disease events which requires hospitalization and could generate extra costs for the health insurance. There is no French studies analyzing the additional costs induced by VTE and cancer. The objective of this study is to provide an estimation of the additional cost induced by VTE + cancer from the analysis of hospital stays extracted from PMSI 2013 (French Hospital Database) for 4 types of cancer (breast, lung, hepatocellular carcinoma and colon). METHODS: A crossed approach of Principal Diagnosis (DP) and Comorbidities (DAS) was performed to identify all stays combining VTE and cancer. The analysis is divided into 3 parts: a descriptive approach of hospital stays for VTE + cancer, an analysis by severity level of DRG and an economic valorization based on the National Cost Scale. It was not achieved PMSI extraction to create a comparison population for each type of cancer because the creation of such a population could be a mood point, in particular because of other comorbidities may also generated additional costs (eg infection). Public ATIH database was used. The essential approach of this study is based on analysis of the distribution of stays according to levels of severity DRG. RESULTS: