UTILIZATION OF MEDICATIONS FOR SECONDARY PREVENTION OF CARDIOVASCULAR MORBIDITY AND MORTALITY IN MEDICARE BENEFICIARIES

Author(s)

Olvey EL1, Bootman JL1, Armstrong EP2, Nolan PE1, Sherrill D3, Denninghoff K4, Skrepnek GH11University of Arizona, College of Pharmacy, Tucson, AZ, USA, 2University of Arizona, Tucson, AZ, USA, 3University of Arizona, Mel & Enid Zuckerman College of Public Health, Tucson, AZ, USA, 4University of Arizona, Department of Emergency Medicine, Tucson, AZ, USA

OBJECTIVES: To report the utilization of guideline recommended statins, angiotensin converting enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB), and beta-blockers (BB) for secondary prevention of coronary heart disease (CHD) in community-dwelling Medicare beneficiaries ≥65 years. METHODS: Data from the 2004-2006 Medicare Current Beneficiary Survey were utilized to conduct a retrospective, cross-sectional study.  Community-dwelling Medicare beneficiaries ≥65 years of age indicating a past history of CHD or myocardial infarction were selected.  All commercially available statins, ACEIs/ARBs, and BBs in the US, including brand, generic and combination products, were included.  Medication possession ratio (MPR) was the proxy used for adherence, defined as ≥80% MPR.  Descriptive statistics were used with sampling weights applied for all analyses. RESULTS: The 2004, 2005 and 2006 sample sizes were 2,338,741, 2,186,251, and 2,159,661, respectively.  At least one prescription medication for statins was reported in 62.2%, 62.4% and 64.0% of beneficiaries in 2004, 2005 and 2006.  Adherence in beneficiaries having at least one prescription for a statin was 44.6% in 2004, 47.4% in 2005, and 54.5% in 2006.  In 2004, 2005, and 2006, 59.1%, 55.3%, and 56.5% of beneficiaries reported at least one prescription for an ACEI/ARB with 45.1%, 40.8%, and 57.2% of beneficiaries with at least one prescription for an ACEI/ARB achieving ≥80% adherence.  At least one BB prescription was reported for 57.3%, 58.4%, and 61.5% of beneficiaries in 2004, 2005, and 2006, respectively.  Adherence to BBs for those beneficiaries reporting at least one BB prescription was 35.1%, 44.5%, and 53.6% in 2004, 2005, and 2006, respectively.  The percentage of beneficiaries reporting at least one prescription for all three medications in 2004, 2005, and 2006 were 27.5%, 26.3% and 29.4%. CONCLUSIONS: Utilization of guideline recommended pharmacotherapies for secondary prevention of cardiovascular morbidity and mortality in this US Medicare patient population have improved over time but remain suboptimal.

Conference/Value in Health Info

2012-06, ISPOR 2012, Washington, D.C., USA

Value in Health, Vol. 15, No. 4 (June 2012)

Code

PCV77

Topic

Patient-Centered Research

Topic Subcategory

Adherence, Persistence, & Compliance

Disease

Cardiovascular Disorders

Explore Related HEOR by Topic


Your browser is out-of-date

ISPOR recommends that you update your browser for more security, speed and the best experience on ispor.org. Update my browser now

×