OBJECTIVES: This session intends to identify patients’ preferences for receiving reminders when participating in clinical trials. Results of a survey on patient experiences will be reported. Recommendations for developing reminder strategies will be provided with the intention of enhancing the patient’s experience and compliance. METHODS: An internet survey was administered to patients (in December 2010) who participated in at least one clinical trial with patient diaries in the past two years. The survey focused on patients’ perceived experiences and preferences with patient diaries/ePRO, and how patient diary methods could be improved. This session will focus on the questions relating to patient reminders–specifically relating to preferences for how reminders were sent/received, activities for which reminders were found most useful, frequency of reminders, etc. RESULTS: Reminder methods patients preferred most were email and text messages. Two areas patients preferred to be reminded about were any action required of them as part of their clinical trial participation and when they were required to record an electronic-diary entry. When patients were asked about how often they wanted to receive reminders, the most frequent responses included whenever there was new information related to their trial participation and once per day. Patients also provided suggestions for reminders in future trials. CONCLUSIONS: The results focus on what patients are telling industry what they do/do not want in terms of reminders; these perspectives should be accounted for to enhance the patient journey and compliance. If industry implements the reminder strategy wrong (for instance, annoying patients by reminding them too frequently), that may actually impact compliance negatively. Remind patients when necessary/not too often. Remind patients in ways they will be able to best receive/notice them. Appropriate use of reminders drives compliance and incorporating patient preferences will not only improve compliances rates, but will also enhance the patient’s experience.