OBJECTIVES:  To determine whether culturally relevant diabetes education is warranted for US geographies with high Hispanic populations.  Examine differences in diabetes metrics between pharmacies located in zip codes with high versus low Hispanic populations.  Analyze prevalence, incidence, new patient age, therapy adherence, inferred disease severity, and inferred disease progression. METHODS: Catalina Health™ receives a nationally representative sample of pharmacy data containing 40% of all US retail prescription volume and 130 million unique patient ID’s.  The data is HIPAA compliant, updated daily, longitudinal, and not projected.  Select a cohort of patients (40% random sample) filling diabetes scripts in the 1st quarter of 2007 in zip codes with low (