OBJECTIVES: Patient reported outcomes (PROs) have become an important component of many clinical studies. The use of ePRO as a data collection method can alleviate the potential burden experienced by patients and/or sites.  The purpose of this survey study was to capture current PRO data collection trends and summarize these findings side-by-side with results from a previous PRO data collection survey. METHODS: Industry professionals were invited to complete a web-based survey fielded in late 2011 and early 2012. This survey included questions on professional demographics, experience using PROs (and ePROs) by study type and experience with ePRO technologies.  Responses were analyzed descriptively. RESULTS: To date, 54 industry professionals completed the 2011-2012 survey.  Fifty nine percent of respondents were from pharmaceutical companies, biotech (26%), medical device (9%), and other (6%). While 49% of respondents in the 2010 survey had previous PRO study experience, 60% of respondents in the current survey had previous PRO experience.  The proportion of respondents with prior ePRO experience, however, was similar across the two surveys (51% in 2010 and 54% in 2011-2012).  Hand-held device (tablet, PDA) was the most common ePRO technology (71% in 2011, 64% in 2010), followed by interactive voice response (47% in 2011, 60% in 2010), and interactive web-response (29% in 2011, 51% in 2010).  Among those with prior ePRO exposure in 2011 and 2010, respectively, 59% and 86% strongly agreed/agreed they would use ePRO in future studies. Among those who never used ePROs, 58% in 2011 and 50% in 2010 indicated they would likely use ePROs in future studies. CONCLUSIONS: Results from this survey suggest that ePRO use continues to gain moderate acceptance among industry professionals. These findings, however, were based on a limited sample size. Future surveys should be administered to allow future trends in ePRO use to be observed over time.