OBJECTIVES The current study looks to explore young children from high-risk families in the Taipei City setting. High-risk social welfare intervention was investigated. First, differences between enrollees and non-enrollees for medical subsidy program among high-risk family whose cases were started in 2009 or 2010 will be looked at. Second, the study will try to determine the social welfare intervention’s effectiveness in increasing application for medical subsidy program and finding any predictors which may have helped or harmed application for enrollment.  METHODS The study sample included under 6 year old children high-risk families (n=199). High-risk family database and medical subsidy database were linked. Differences between high-risk subsidy enrollees (n=87) and non-enrollees (n=112) and effectiveness of a social welfare intervention in increasing subsidy application were investigated in a pre-post analysis of high-risk social welfare intervention. Individual level as well as relative residential level characteristics were explored. RESULTS Medical subsidy enrollment was correlated with younger age at time of a high-risk intervention and relative district level variables. Pre-post comparison suggests high-risk interventions significantly increased subsidy application by 7.4%. Logistic regression indicates older age at time of intervention was associated with 40% less chance of application.  CONCLUSIONS The study provides empirical evidence for potential effects of a high risk social welfare intervention on the accessibility to healthcare. Findings also show where policy makers can improve intervention in order to address the needs children at-risk, especially for different age groups.