OBJECTIVES - This paper focuses on this knowledge gaps for informed decision-making and identifies key barriers in uptake PCV in India. METHODS - Qualitative interviews were conducted with pediatricians registered with Indian Academy of Pediatrics to generate evidence on perspective and practices regarding the PCV. A multi-level stratified sampling was applied to identify pediatricians across 12 metropolitan cities. The analysis was conducted using standard qualitative techniques to identify key domains, words, phrases and concepts from respondents. Quantitative variables are reported as mean and proportions.  RESULTS -Majority (67.7%) of pediatricians advice for PCV to all whereas 32.2% advice PCV only to those who can afford. Around half (50.8%) have no specific preference and recommend any PCV vaccine where as 28.0% recommend PCV13. Main reason for acceptance of PCV were educated and informed clients (50.8%) followed by pediatrician’s advice and counseling (25.4%) whereas main reason for denial was price of vaccine (97.3). In addition, majority (74.1%) of pediatricians wanted PCV to be included into UIP whereas (17.7%) didn’t and (8.0%) were not sure.  CONCLUSIONS - Pediatricians should put efforts to increase awareness about vaccine preventable disease among their clients and can facilitate bridge the knowledge action gap by helping their clients to make informed decision with regards to uptake of newer vaccines.