OBJECTIVES ：To evaluate the cost-effectiveness of commonly used antimicrobial regimens in treatment of Community-acquired Pneumonia (CAP) in China. METHODS ：This was a retrospective study of CAP patients who received different antibiotic drugs during their hospitalization in a 1^st Class, Grade A hospital in Shenyang, Liaoning between January 2011 and June 2012. Cost-effectiveness analysis was performed for the common therapeutic regimens based on both clinical practice and the main recommended antibacterial treatment of CAP from the perspective of society as a whole. For the sensitivity analysis, we used a relative measurement method and an absolute measurement method to test the strength of the study’s conclusions over a range of assumptions. RESULTS ：