BASELINE PATIENT CHARACTERISTICS OF A PROSPECTIVE OBSERVATIONAL STUDY TO EVALUATE THE CARE MAP OF WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS (PMO) IN SWITZERLAND (CAMPOS)
Author(s)
Lippuner K1, Lamy O2, Theiler R3, Merlin C4, Pendl G5, Del Ponte A5, Murigande C5, Schwenkglenks M6
1University of Bern, Bern, Switzerland, 2Lausanne University Hospital, Lausanne, Switzerland, 3Triemli Hospital, Zurich, Switzerland, 4Rheumatology Practice and Osteoporosis Center, Baden, Switzerland, 5Amgen Switzerland AG, Zug, Switzerland, 6University of Basel, Basel, Switzerland
OBJECTIVES: Report baseline patient characteristics of the CAMPOS study, which is evaluating the PMO care map in Swiss clinical practice. METHODS: Between June 2012„ŸMay 2013, specialist osteoporosis centers operating a DXA machine enrolled women diagnosed with PMO who initiated intravenous (IV) ibandronate or zolendronate, or subcutaneous (SC) denosumab (index date) within 6 months prior to center initiation. Study outcomes are recorded at index date (baseline) and any visit in the 24-month observation period thereafter, as available from routine practice. RESULTS: Twenty-one centers, mainly in urban regions (81%), of a non-academic nature (76%), and specializing in rheumatology (71%), recruited 275 women. Two-hundred-sixty-three met the inclusion criteria and were included in this baseline analysis; 180 (68%) of these received follow-up care at the specialist center and 83 (32%) were referred back to general practice. At baseline, mean (SD) age was 70.9 (9.7) years and mean time since diagnosis 5.4 (5.4) years (n=248). The following diagnostic parameters and risk factors were assessed at the time of PMO diagnosis: prior osteoporotic fracture, 258 [94%] patients, with 60% reporting this risk factor; DXA bone mineral density (BMD) scan, 255 (97%) patients (hip and either lumbar spine or forearm BMD measured in 231 [88%] patients), mean (SD) BMD T-scores at the femoral neck and lumbar spine -2.34 (0.79; n=230) and -2.89 (1.28; n=232), respectively; calcium and vitamin D status, 260 (99%) patients; fracture history, 258 [98%] patients. CONCLUSIONS: In the current study, prevalent fractures were assessed in almost all women initiating IV ibandronate or zolendronate, or SC denosumab, and the majority reported at least one prior fracture. Calcium and vitamin D status, DXA BMD scans and/or fracture history were also routinely assessed at PMO diagnosis.
Conference/Value in Health Info
2014-11, ISPOR Europe 2014, Amsterdam, The Netherlands
Value in Health, Vol. 17, No. 7 (November 2014)
Code
PMS93
Topic
Epidemiology & Public Health, Health Service Delivery & Process of Care
Topic Subcategory
Hospital and Clinical Practices, Public Health
Disease
Musculoskeletal Disorders