OBJECTIVES: To assess and evaluate the association between pharmacists’ attitude, perceived preparedness, and willingness to prepare regarding the issue of escalating pharmaceutical demand due to the aging baby boomers. METHODS: This was a non-experimental, cross-sectional, field study design. The study sample consisted of registered pharmacists’, practicing in chain and independent community pharmacy stores in Houston and surrounding areas. A self-administered survey questionnaire based on the proposed model for the study was developed to address the study objectives. Descriptive analysis followed by paired t-tests (dependent sample); wilcoxon signed-rank tests (independent sample) and spearman correlation analysis were performed to assess the study objectives.  RESULTS: A total of 117 pharmacists’ responded with an overall response rate of 49.8%. Mean age of the respondents was 41.1 (±11.1) years, with majority being females (51.7%), African Americans (41.0%), having an average experience of 13.6 (SD ± 11.6) years, working in chain pharmacy setting (77.8%), having a PharmD degree (55.7%) and working full time (91.4%).  Non-respondents matched the sample on the gender (p=0.75) and practice setting (p=0.84). Approximately 60% pharmacists’ rated their current workload level as high, with 92% believing their workload level to significantly increase given the rise in the aging baby boomer population over the next two decades. However, nearly 56% pharmacists’ believed that the potential changes in workload will not affect their job, patient-care and health related outcomes. Also, approximately 83% pharmacists’ agreed to be prepared and willing or very willing to take action, whatever it may be, to better prepare themselves for the aging baby boomer population.  CONCLUSIONS: Pharmacists’ attitude and perceived preparedness were found to be significantly associated with their willingness to prepare for the aging baby boomer population. Further studies are required to assess the effect of various covariates on pharmacist’s willingness to prepare for the aging baby boomer population.