OBJECTIVES: Access to multi-country physician panels is an alternative option to recruit medical sites for health outcome or post-approval studies, compared to the conventional approach of individually recruiting clinical expert sites. The objective of our study was to assess the potential of physician panels for site recruitment. METHODS: In 2012, a representative survey among members of a managed physician panel (All Global’s managed panel of ophtalmologists in US, UK, GER, FR, IT and SP) was conducted. The survey assessed the willingness of the physicians to participate in post-approval studies. Information about former participation in those studies and commitment to special requests for post-approval studies (e.g. ethical committee involvement, advent reporting to sponsor, security of patient’s informed consent) were also collected. RESULTS: 200 opthalmologists participated in the survey.  Since no special incentive was offered for participation the response rate of more than 25% was satisfactory. 79 (39,5%) of the physicians formerly participated in clinical trials and 95 (47,5%) in post-approval studies. 54,5% of the ophtalmologists were willing to participate in future studies. More than 80% of this group was ready to ask their hospital or other legal authorities for permission to participate in studies of this kind, to report serious adverse events to the sponsor of the study and to ask patients for written informed consent. CONCLUSIONS: Managed physician panels are a valuable alternative option to recruit medical sites for post-approval or health outcome studies. Every second ophtalmologist from panels is experienced in this kind of studies and most of them are willing fullfil all necessary legal and quality requirements. In addition to timing and cost factors, an adavantage of physician panels is the better representation of daily medical routine-practice, adding to the epidemiological validity of respective projects.