PHYSICIAN PANELS SUPPORTING CLINICAL TRIALS AND POST-APPROVAL STUDIES IN ONCOLOGY- A WILLINGNESS-TO-PARTICIPATE STUDY
Author(s)
Potthoff P*1;Brown C2;Güther B3, Eichmann F3 1Kantar Health GmbH, München, Germany, 2All Global, London, United Kingdom, 3Kantar Health Germany, Munich, Germany
Presentation Documents
OBJECTIVES: Clinical oncology research projects require participation of oncologists and/or hematologists to recruit patients and/or assess clinical outcomes. A variety of methods is used to recruit office or hospital based physicans. Specifically for studies with an epidemiological aspect, the study should not rely on the typical clinical expert sites, thus, alternative recruitment pathways are increasingly considered. The objective of our study was thus to assess the benefits of using physician panels for site recruitment. METHODS: In 2012, a representative survey among members of a managed physician panel (All Global’s managed panel of oncologists and hematologists in US, UK, GER, FR, IT and SP) was conducted. A Sample of oncologists and hematologists was selected. The panel was stratified by country and within the strata physicians were randomly selected. 335 out of 1.303 oncologists and hematologists in the sample (25,7%) reported about their former experience with clinical trials and post-approval studies, their willingness to participate in future studies and their adherence to aspects of GCP rules. RESULTS: 284 (84,7%) of the physicians have formerly participated in clinical trials and 276 (67,2%) in post-approval studies. 88,9% of the experienced oncologists and hematologists were willing to participate in future studies. More than 80% of this group was ready to be named as principal investigator to an ethical committee, to report serious adverse events to the sponsor of the study and to ask patients for written informed consent. No substantial difference between countries was detected. CONCLUSIONS: Since no special incentive was offered for participation the response rate was satisfactory Managed oncologist panels are a cost-effective, experienced and high-quality source for post-approval studies. Elaborated management processes in multi-country panels guarantee a constant quality of the panel over geographies.
Conference/Value in Health Info
2013-11, ISPOR Europe 2013, The Convention Centre Dublin
Value in Health, Vol. 16, No. 7 (November 2013)
Code
PRM17
Topic
Methodological & Statistical Research
Topic Subcategory
Confounding, Selection Bias Correction, Causal Inference
Disease
Oncology