OBJECTIVES: Reversal of the residual effect of rocuronium or vecuronium by neostigmine may be slow and associated with side-effects. Sugammadex, a selective relaxant binding agent, encapsulates rocuronium to provide for a rapid reversal of residual neuromuscular blockade. Also, postoperative residual neuromuscular block can reduce delay of awakening, recovery, and dissatisfaction of patient. The aim of this study is to evaluate the willingness-to-pay (WTP) of sugammadex for effectiveness and safety using a contingent valuation method. METHODS: A total of 505 adult general population and 60 experts (anesthesiologist and surgeon) participated in a face-to-face survey. The respondents were surveyed separately each scenario of moderate and deep blocks for surgery. The scenario was designed to provide information concerning reversal time on neuromuscular block, adverse reaction of PRNB, and quality of surgery or recovery. The out-of-pocket WTP for sugammadex was utilized open answer. RESULTS: In general population, WTP values for sugammadex were 81,768 Korean won (KRW) in moderate block and 128,622 KRW in deep block. The same sample answered 89,017 KRW and 141,536 KRW for WTP for their family members in moderate block and deep block, respectively. Experts were estimated the WTP of 99,417 KRW in moderate block and 153,250 KRW in deep block. For patients, experts suggested that 82,517 KRW and 132,517 KRW were appropriate WTP. The WTP was statistically significantly higher in the general population who had been taken operation and older than their counterparts. CONCLUSIONS: The WTP for sugammadex was ranged the 81,768 to 99,417 KRW in moderate block, and the 128,622 to 153,250 KRW in deep block. The WTP of general population for their family members was higher than the WTP for their own, and the expert’s WTP was higher than their patients.