OBJECTIVES: Cystitis is one of the most common bacterial infections in women. Cystitis is acute or chronic bladder inflammation. It manifests itself by a frequent desire to urinate, accompanied by a burning sensation when passing urine.  To evaluate the impact of preventive treatment of patients suffering from recurrent cystitis with titrated dried cranberry extract. METHODS: Pragmatic, longitudinal and prospective follow-up carried out by Urologists within the framework of their everyday professional activities. RESULTS: A total of 120 patients with a mean age of 53.3 ± 18.9 years were enrolled by 43 urologists throughout France. These patients were monitored for 7 months (median) by the urologist.  5 symptoms were evaluated every three weeks by the patient:  frequency , urgency of urination, burning sensation on urination,  inability to empty the bladder completely, sensation of heaviness in the lower abdominal area.   These symptoms were also graded by the patient according to the intensity experienced multiplied by the frequency.  On enrolment, the scores for each symptoms were 6.4; 6.6; 5.3; 3.1; 4.2 respectively. The overall score was 27.6 According to data collected by the patients, the overall symptom score fell significantly (p <0.001) between enrolment and 6 months of treatment.   At 6 months (24 weeks of treatment) the score for each symptom was 2.1; 2.6; 1.8; 0.8 and 1.2 respectively, therefore the overall score was 9.2. The overall score progression is significant (p <0.0001), and in addition the progression of each symptom is also significant. The prevalence at 6 months is 27.8% (versus 98.3%) at enrolment. CONCLUSIONS: Recurrent cystitis generally requires prophylactic antibiotic medication for several months. The initiation of such treatment should take into account the worrying increase in antibiotic resistance. The prevalence of  urinary problems in subjects with recurrent cystitis was reduced by 3 after six months of treatment with dried titrated cranberry extract ( 98.3% versus 27.8%).