OBJECTIVES: To assess preferences, using the time trade-off (TTO), regarding frequencies of having to go for a doctor’s visit to receive pharmacological injections for the treatment of schizophrenia.  METHODS: A survey was conducted in Sweden; respondents including 259 patients with a serious mental disorder, 263 relatives of individuals suffering from a serious mental disorder, and 528 people sampled from the general population were recruited for the purpose of this study. A time trade-off (TTO) study design was used to elicit the utility of decreasing the frequency of necessary doctor visits. Average utilities were calculated for each health state for each respondent group. The marginal disutility of an additional yearly visit to the doctor was estimated using a standard OLS regression with an intercept. Bootstrapping was utilized to compute 95% confidence intervals around utilities and marginal disutilities.  RESULTS: The marginal disutility of an additional doctor visit was found to be 0.0041 for patients, 0.0022 for relatives, 0.0017 for the general population and 0.0022 for an average respondent. For an average respondent across all groups, this corresponded to an additional utility of 0.031 between having to visit the doctor for an injection once a month versus every other week and 0.048 between having to visit the doctor for an injection once every 3 months versus every other week. CONCLUSIONS: The results are suggestive of a general trend of increased reported disutility for a higher number of doctor visits for an injection per year across all respondent groups.