OBJECTIVES: To describe demographical and medical characteristics of patients treated with bi- or multi- antihypertensive therapies and to outline the link between therapeutic scheme, blood pressure control and patients co morbidities. METHODS: A retrospective study was undertaken, based on the IMS Lifelink Electronic Medical Records database (Disease Analyzer), investigating age, gender, blood pressure control and co morbidities according to the number and type of associated antihypertensive therapies. RESULTS: A total of 13,618 patients, treated by bi- or multi- antihypertensive therapies and for whom blood pressure levels were available have been included in a 2008 study cohort (mean age = 66.8, 48% men). Respectively 39% and 58% of patients had a controlled blood pressure depending on the threshold of the control (<140/90 or =140/90); prescribing 4 or more associated antihypertensive does not seem to increase the percentage of controlled patients.