OBJECTIVES: To evaluate disease-specific quality of life (QoL) in children with asthma according to patients’ and their parents’ perspective. METHODS: Hungarian version of the Standardised Paediatric Asthma Quality of Life Questionnaire (PAQLQ(s)) and the Paediatric Asthma Caregiver’s Quality of Life Questionnaire (PACQLQ) were completed. The minimal important difference in the PAQLQ total score is 0.5 on the 7-point Likert scale, higher scores indicate better QoL. Asthma control was assessed by Asthma Control Questionnaire (ACQ); Forced Expiratory Volume in 1 second (FEV1) was measured via spirometry RESULTS: A total of 125 children (7-17 years of age) and their caregivers completed the questionnaires. Overall PAQLQ score was 5.74+0.97, overall PACQLQ score was 5.32+1.22 (r=0.83), mean ACQ score was 1.65+0.8 and mean FEV1 was 100.71+14.91. PACQLQ scores were statistically (p=0.001) and clinically significantly lower, than PAQLQ scores. Correlations between FEV1 and overall score of PAQLQ(s) (r=-0.15) and overall PACQLQ score (r=-0.005) were weak and not significant. The association between ACQ and total score of PAQLQ(s)(r=-0.64, p=0.01) was moderate. CONCLUSIONS: Our participants had poor asthma control despite their good lung function. Weak relationship was found between spirometry and QoL according to patients’ and caregivers’ opinion; however QoL correlated only moderately with the level of asthma control. PAQLQ is able to detect small but clinically important changes that children experience as a result of the treatment or as a part of the natural fluctuation of their asthma, it provides additional valuable information for clinical practice; children aged over 7 can provide reliable data on their Qol, where as parents often do not rate their children’s Qol appropriately.