OBJECTIVES: Neuropathic pain (NeP) is a chronic condition endured by those who have suffered damage to their somatosensory system. This damage can often result from various concomitant diseases. The condition can have a severe effect on the level of quality of life (QoL). The purpose of this abstract is to investigate the level of pain and impact on QoL of patients who suffer from NeP relative to recorded pain levels METHODS: Data were drawn from the 2012 Adelphi NeP Disease Specific Programme, a cross sectional survey involving 121 primary care physicians and 292 specialists across France, Germany, Italy, Spain and UK. Physicians provided data on diagnosis and treatment patients, patients filled a self-completion questionnaire which included the EQ-5D and Brief Pain Inventory questionnaires (BPI; Interference measure). Patients were split into those who have peripheral (N=2033), central (N=301) or both peripheral and central (P&C) condition(s) (N=165) and by categorising patients by peripheral conditions causing NeP. RESULTS: A total of 3956 patients were included, of whom 2499 completed both EQ5D and BPI. For patients suffering with, peripheral, central and P&C, BPI values were 4.34, 4.70 and 4.77 respectively whereas EQ5D values were 0.591, 0.535 and 0.486 respectively. All differences between peripheral, central and P&C were statistically significant (P <0.01).  Average scores across the entire sample were EQ-5D 0.577, BPI 4.41. Certain conditions were associated with lower QoL and greater pain, notably radiculopathy (N=472, EQ-5D 0.553, BPI 4.66), fibromyalgia (N=189, EQ-5D 0.514, BPI 5.06) and alcoholism (N=84, EQ-5D 0.544, BPI 4.93) all p<0.01 compared to population means. CONCLUSIONS: These data show an inverse relationship between level of pain and the QoL experienced by patients using the EQ-5D and BPI. This was particularly evident amongst patients with P&C and within NeP caused by radiculopathy, fibromyalgia and alcoholism. Better pain control would therefore lead to improvements in QoL.