OBJECTIVES: To value SF-12v1 outcomes from the perspective of US adults METHODS: The paired comparisons of the SF-12v1 items were incorporated into a larger, online survey of US health preferences using an invitation-only panel of US respondents. This pivoted discrete choice experiment (DCE) collected 28,080 responses on 408 pairs from 936 respondents. The quantal response model includes an additive multi-attribute regression within a stacked logit distribution to allow for excess kurtosis due to satisficing. RESULTS: On a quality-adjusted life year scale, 30 out of 31 decrements were significantly non-zero at 0.05 significance level. The only insignificant decrement, LE2, represented the decrease in energy from “You have a lot of energy all of the time” (i.e., manic) to “You have a lot of energy most of the time.” The value of pits was 0.1532 QALY (95% CI 0.1022,0.1970) and was significantly better than dead (0). CONCLUSIONS: This is the first national valuation study of the SF-12v1 descriptive system. Instead of reducing domains of complex descriptive systems to single items (e.g., SF-36v1), DCE allows for choice-based valuation of all outcomes, regardless of the number of items.