OBJECTIVES: The aim of the current study is to utilize two different methodologies to estimate the prevalence and burden of type 2 diabetes (T2D) and obesity among the adult population in France. METHODS: Two separate representative data sources were used for the adult French population. Data from the French respondents of the EU National Health and Wellness Survey (NHWS) (N=15,051) and the OBEPI survey (N=25,286) were used. The NHWS is an internet-based annual survey and the OBEPI is a mailed survey conducted every three years, validated by the French authorities.  Prevalence information for T2D, comorbid treatments, and BMI were analyzed using both data sources. The humanistic and economic burden of T2D was analyzed only from the NHWS data. RESULTS: From NHWS, 44.3% of respondents from France were male and the average age was 45.1 years (SD=15.5). From OBEPI, 47.8% were male and the average age was 48.2 years (SD=17.8).  A total of 30.5% (OBEPI=31.9%) and 15.6% (OBEPI=14.5%) of the French population were estimated to be overweight and obese, respectively. A total of 4.4% (from NHWS) and 4.8% (from OBEPI) of the adult French population reported suffering from T2D. Among these patients, 15.1% and 80.5% were taking an insulin and oral treatment, respectively (12.4% by OHA+insulin and 76.0% by OHA only as estimated by OBEPI).  From NHWS, a significant burden was observed among patients with T2D as they reported significantly lower levels physical quality of life (using the SF-12v2; 42.6 vs. 50.1, p<.05) and significantly greater work impairment (26.7% vs. 18.2%, p<.05) and physician visits (8.7 vs. 5.5, p<.05). CONCLUSIONS: Both internet and mailed survey methodologies provided consistent prevalence estimates of diabetes and obesity among the French population. Further, despite the high prevalence of treatment, significant effects are observed on health outcomes among T2D patients, highlighting the unmet need.