RETROSPECTIVE PRESCRIPTION ANALYSIS OF DEMENTIA IN A SOUTH INDIAN PSYCHIATRIC HOPITAL
Author(s)
Nagappa AN1, Gayathri P2, Kachappally S3, Devaramane V4, Bhandary V4, Balkrishnan R51Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India, 2Manipal Univeristy, Manipal, India, 3Manipal Univeristy, Manipal, Karnataka, India, 4Dr A V Baliga
OBJECTIVES: The aim of the study is to investigate the use of medications prescribed to dementia patients in a secondary care hospital METHODS: A retrospective chart review method was performed in patients with diagnosis of dementia for the duration of six months. The relevant information related to the study objectives such as demographic details, type of medication, dose and frequency etc has been collected. The patient who has come for follow up during the study period has also been included to find out any outcomes RESULTS: Out of 30 patients included in the study, 63.3% were females and 36.7% were males. Most of the patients belong to the age group of 60-80 years. On prescription pattern analysis, it was found that 86.7% of the patients were on donepezil, cholinesterase inhibitors. Among antipsychotics Quetiapine was the most commonly used atypical antipsychotic. Five (16.7%) patients were on memantine where as 4 (13.3%) patients were on combination of donepezil and memantine. On follow up it was found that in three patients who was on donepezil has been changed to a combination of donepezil and memantine. Whereas in other two patients the dose of the donepezil has been increased. As a result of improvement seen in two patients donepezil was stopped and memantine was continued and in the other patient who has been on the combination of donepezil and memantine has been tapered gradually and stopped as there was a marked improvement seen. In this study, we could also find prescription error in 13.33% (4) of the prescription related to the overdose of donepezil CONCLUSIONS: In a developing country like India, dementia still remains as an underrecognized public health burden. Our study depicts a picture of usage of antidementia drugs, it shows that further research to be done in dementia patients related to cost effectiveness
Conference/Value in Health Info
2011-11, ISPOR Europe 2011, Madrid, Spain
Value in Health, Vol. 14, No. 7 (November 2011)
Code
PMH78
Topic
Health Service Delivery & Process of Care
Topic Subcategory
Prescribing Behavior
Disease
Mental Health, Neurological Disorders