IMPACT OF TWO DIFFERENT TREATMENT APPROACHES ON EPIDEMIOLOGY OF INHIBITOR HEMOPHILIA IN RUSSIA

Author(s)

Vorobyev PA1, Borisenko O1, Krasnova L2, Zhulyov Y3, Bezmelnitsyna L11Russian Society for Pharmacoeconomics and Outcomes Research, Moscow, Russia, 2Moscow State Medical University named after I.M.Sechenov, Moscow, Russia, 3Russian Hemophilia Society, Mosc

OBJECTIVES: Russian Society of Pharmacoeconomics and Outcomes Research jointly to Russian Hemophilia Society carried out postal and telephone health survey of all known Russian patients with hemophilia in the period 2009-2010. Aim of the study was to assess health status, treatment patterns and quality of life in patients with inhibitory form of hemophilia. METHODS: Postal and telephone health survey. The questionnaire contained questions on number of bleeding in last month, number of injections of clotting factors per month, names of used medications, number of ambulance calls and hospitalizations. The patients’ education level and employment data was collected. Analysis of experimental data was performed with such statistical parameters as χ² and Student’s criteria. RESULTS: The presence of antibodies was detected in 60 patients with hemophilia A (47 patients (78,3%) were adults, 4 (6,7%) – adolescents, 9 (15%) - children upward 11 years old). All patients were divided into 3 subgroups: 31.7% patients received immunological tolerance (IIT), 31.7% - therapy with NovoSeven, 36.6% - mixed therapy. During one month bleeding was indicated in 78.9%, 100%, 90.9% patients in 3 subgroup respectively; clotting factor VIII was used in 100%, 73.7%, 95.4% patients respectively; emergency calls were made by 10.5%, 5.3%, 22.7% patients; 26.3%, 31.6%, 13.6% patients were hospitalized; 63.2%, 68.4%, 72.7% patients made injections of clotting factor themselves. CONCLUSIONS: The rate of ambulance calls and hospitalizations was comparatively low. Most patients made injections of clotting factor themselves.

Conference/Value in Health Info

2011-11, ISPOR Europe 2011, Madrid, Spain

Value in Health, Vol. 14, No. 7 (November 2011)

Code

PSY52

Topic

Health Service Delivery & Process of Care

Topic Subcategory

Treatment Patterns and Guidelines

Disease

Systemic Disorders/Conditions

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